Recent advances in Gd-chelate based bimodal optical/MRI contrast agents

Recent Advances in PET-MR Hybrid contrast agent

Introduction: All of the Imaging modalities have advantages and disadvantages alone. So if we want to have the best and perfect image, combining these modalities produces something we desired. PET-MR images consist of morphologic and metabolic data. MRI and PET provide high spatial and contrast resolution and high sensitivity and molecular information respectively. Hybrid PET-...

Recent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning

Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...

Recent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning

Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...

Multimeric Gd-based Contrast Agents for high field MR-imaging

Introduction. MR imaging is increasingly moving to higher fields as the majority of MRI scanners used in clinics work at 3 T. Imaging at high fields brings greater signal-to-noise ratio (SNR) and its concomitant benefits of higher spatial resolution and/or reduced acquisition times. Currently employed Gd-based contrast agents are small, fast tumbling molecules with low relaxivity that decreases...

Development of Gd@C60 Based MRI Contrast Enhancing Agents